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How to Diagnose Brugada Syndrome: ECG Watch Guide

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How to Diagnose Brugada Syndrome: ECG Watch Guide

Brugada syndrome is an inherited heart disease that creates the characteristic Brugada ECG pattern on a standard 12-lead ECG in leads V1 and V2. This pattern can also be captured using watches.

ECG brugada pattern, Type 1

Brugada syndrome causes ventricular arrhythmia. During arrhythmia, the heart cannot adequately pump blood, leading to cardiac arrest, which can sometimes be life-threatening. Triggers for arrhythmia may include fever and certain medications.

Brugada syndrome accounts for 4-12% of all sudden cardiac deaths. The treatment is implantation of a defibrillator.

Can ECG watches diagnose Brugada syndrome?

Yes.

However, ECG watches should be placed in the 2nd intercostal space to the right and left of the sternum and two ECG recordings should be taken. In a 12-lead ECG, leads V1 and V2 are conventionally placed at the 4th intercostal space.

Diagnosing Brugada Syndrome with ECG Apple Watch

If the Brugada ECG pattern is present in at least one ECG recording, contact a cardiologist.

What is Brugada syndrome?

Brugada syndrome is a congenital genetic heart disease that causes ventricular arrhythmia. During arrhythmia, the heart cannot adequately pump blood, which may manifest as:

Brugada syndrome exhibits a typical Brugada ECG pattern in leads V1 and V2 of the standard 12-lead ECG. In cases of unclear findings or suspicion based on history, leads V1 and V2 are shifted higher to the 2nd intercostal space to better capture the Brugada pattern.

Brugada syndrome is treated with the implantation of a defibrillator, which immediately detects ventricular arrhythmia and terminates it with an electric shock. The patient feels the shock as a "kick" to the chest.

Epidemiology

The incidence of the Brugada ECG pattern is 1:2000.

70% of patients are asymptomatic.

It is 10 times more common in men.

The risk of symptoms is 10% over 2.5 years.

Brugada pattern vs. Brugada syndrome

The Brugada pattern affects 1/2000 people. The patient exhibits this pattern but is asymptomatic. It may be detected, for example, during preoperative or preventive examinations. 70% of patients with the Brugada pattern are asymptomatic. The Brugada pattern may appear and disappear during the day, so an ajmaline test is used when there is suspicion of Brugada syndrome.

Brugada syndrome affects 5/10,000 people. The patient exhibits the Brugada pattern on ECG and is symptomatic.

Symptomatology

The risk of symptoms in patients with the Brugada pattern is 10% over 2.5 years.

Symptoms arise due to ventricular arrhythmia, during which the heart cannot adequately pump blood.

Symptoms are more common at night and during sleep.

Most common symptoms:

Brugada syndrome accounts for 4-12% of all sudden cardiac deaths.

It is very common in Japan and Southeast Asia, where it is referred to as:

What triggers symptoms?

The most common trigger of ventricular arrhythmia, which causes symptoms in Brugada syndrome, is fever. Therefore, it should be immediately reduced, for example, with paracetamol.

Other triggers of arrhythmia include:

How is Brugada syndrome diagnosed?

Brugada syndrome is diagnosed using a standard 12-lead ECG, which is commonly performed in outpatient clinics or hospitals.

A typical Brugada ECG pattern must be present in leads V1 and V2.

In cases of unclear findings or suspicion based on symptoms, leads V1 and V2 are shifted higher to the 2nd intercostal space to better capture the Brugada pattern.

If there is a high suspicion of Brugada syndrome and the patient does not have the Brugada pattern in leads V1 and V2 or in the 2nd intercostal space, an ajmaline test is performed in the hospital. During ajmaline infusion, ECG is continuously monitored, and if the Brugada pattern appears in leads V1 and V2, the test is positive.

ECG watches and Brugada syndrome

Brugada syndrome, specifically the Brugada pattern, can also be diagnosed using ECG watches.

The back of the watches is pressed against the chest in two places:

  1. In the 2nd intercostal space 3cm to the right of the sternum, and the index finger of the right hand is placed on the crown of the watch, and an ECG is taken, then
  2. In the 2nd intercostal space 3cm to the left of the sternum, and the index finger of the right hand is placed on the crown of the watch, and an ECG is taken
Diagnosing Brugada Syndrome with ECG Leads from ECG Apple Smartwatch

If the Brugada ECG pattern is present in at least one ECG recording, contact a cardiologist.

Treatment

Essential is the elimination of factors that trigger ventricular arrhythmia, for example, immediately reducing fever with paracetamol.

However, eliminating triggering factors cannot terminate arrhythmia if the patient experiences it. If the arrhythmia persists, sudden death of the patient may occur.

Therefore, definitive treatment is the implantation of a defibrillator under the skin on the chest. It is a device that immediately recognizes ventricular arrhythmia and terminates it with an electric shock, which the patient feels as a "kick" to the chest.

Conclusion

Brugada syndrome can be diagnosed using ECG watches.

The watches are placed in the 2nd intercostal space 3cm to the right of the sternum, and the first ECG is taken.

Then the watches are placed in the 2nd intercostal space to the left of the sternum, and the second ECG is taken.

If the Brugada pattern is present in at least one ECG, contact a cardiologist.

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